[12] Rosenbaum, M., Goldsmith, R., Bloomfield, D., Magnano, A., Weimer, L., Heymsfield, S., et al. Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. Journal of Clinical Investigation. 2005,115:3579-86.

[13] Rosenbaum, M., Vandenborne, K., Goldsmith, R., Simoneau, J. A., Heymsfield, S., Joanisse, D. R., et al. Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects. American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 2003,285:R183-R92.

[14] Hirsch, J., Hudgins, L. C., Leibel, R. L., Rosenbaum, M. Diet composition and energy balance in humans. Am. J. Clin. Nutr. 1998,67:551S-5S.

[15] Rosenbaum, M., Hirsch, J., Gallagher, D. A., Leibel, R. L. Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight. Am. J. Clin. Nutr. 2008,88:906-12.

[16] Rosenbaum, M., Hirsch, J., Murphy, E., Leibel, R. L. Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function. Am. J. Clin. Nutr. 2000,71:1421-32.

[17] Leibel, R. L., Rosenbaum, M., Hirsch, J. CHANGES IN ENERGY-EXPENDITURE RESULTING FROM ALTERED BODY-WEIGHT. N. Engl. J. Med. 1995,332:621-8.

[18] Cornier, M. A., Grunwald, G. K., Johnson, S. L., Bessesen, D. H. Effects of short-term overfeeding on hunger, satiety, and energy intake in thin and reduced-obese individuals. Appetite. 2004,43:253-9.

[19] Uher, R., Treasure, J., Heining, M., Brammer, M. J., Campbell, I. C. Cerebral processing of food-related stimuli: Effects of fasting and gender. Behavioural Brain Research. 2006,169:111-9.

[20] Rosenbaum, M., Sy, M., Pavlovich, K., Leibel, R. L., Hirsch, J. Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli. Journal of Clinical Investigation. 2008,118:2583-91.

[21] Schmid, D. A., Held, K., Ising, M., Uhr, M., Weikel, J. C., Steiger, A. Ghrelin stimulates appetite, imagination of food, GH, ACTH, and cortisol, but does not affect leptin in normal controls. Neuropsychopharmacology. 2005,30:1187-92.

[22] Gilhooly, C. H., Das, S. K., Golden, J. K., McCrory, M. A., Dallal, G. E., Saltzman, E., et al. Food cravings and energy regulation: the characteristics of craved foods and their relationship with eating behaviors and weight change during 6 months of dietary energy restriction. International Journal of Obesity. 2007,31:1849-58.

[23] Chaput, J. P., Drapeau, V., Hetherington, M., Lemieux, S., Provencher, W., Tremblay, A. Psychobiological effects observed in obese men experiencing body weight loss plateau. Depress. Anxiety. 2007,24:518-21.

[24] Farooqi, I. S., Bullmore, E. T., Keogh, J., Gillard, J., O'Rahilly, S., Fletcher, P. C. Leptin regulates striatal regions and human eating Behavior. Science. 2007,317:1355-.

[25] Malik, S., McGlone, F., Bedrossian, D., Dagher, A. Ghrelin modulates brain activity in areas that control appetitive behavior. Cell Metabolism. 2008,7:400-9.

[26] Rodriguez-Rodriguez, E., Aparicio, A., Bermejo, L. M., Lopez-Sobaler, A. M., Ortega, R. M. Changes in the sensation of hunger and well-being before and after meals in overweight/obese women following two types of hypoenergetic diet. Public Health Nutrition. 2009,12:44-50.

[27] Wadden, T. A. TREATMENT OF OBESITY BY MODERATE AND SEVERE CALORIC RESTRICTION - RESULTS OF CLINICAL RESEARCH TRIALS. Annals of Internal Medicine. 1993,119:688-93.

[28] Curioni, C. C., Lourenco, P. M. Long-term weight loss after diet and exercise: a systematic review. International Journal of Obesity. 2005,29:1168-74.

[29] Elfhag, K., Rossner, S. Who succeeds in maintaining weight loss? A conceptual review of factors associated with weight loss maintenance and weight regain. Obesity Reviews. 2005,6:67-85.

[30] Anderson, J. W., Konz, E. C., Frederich, R. C., Wood, C. L. Long-term weight-loss maintenance: a meta-analysis of US studies. Am. J. Clin. Nutr. 2001,74:579-84.

[31] Tsai, A. G., Wadden, T. A. Systematic review: An evaluation of major commercial weight loss programs in the United States. Annals of Internal Medicine. 2005,142:56-66.

[32] Mann, T., Tomiyama, A. J., Westling, E., Lew, A. M., Samuels, B., Chatman, J. Medicare's search for effective obesity treatments - Diets are not the answer. Am. Psychol. 2007,62:220-33.

[33] Speakman, J. R. Thrifty genes for obesity and the metabolic syndrome--time to call off the search? Diabetes vascular disease research : official journal of the International Society of Diabetes and Vascular Disease. 2006,3:7-11.

[34] Prentice, A. M., Rayco-Solon, P., Moore, S. E. Insights from the developing world: thrifty genotypes and thrifty phenotypes. Proceedings of the Nutrition Society. 2005,64:153-61.

[35] Hofbauer, K. Molecular pathways to obesity. International Journal of Obesity. 2002,26:S18-S27.